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Clustered abasic lesions profoundly change the structure and stability of human telomeric G-quadruplexes
Ionizing radiation produces clustered damage to DNA which is difficult to repair and thus more harmful than single lesions. Clustered lesions have only been investigated in dsDNA models. Introducing the term ‘clustered damage to G-quadruplexes’ we report here on the structural effects of multiple te...
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| Veröffentlicht in: | Nucleic Acids Res |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5416849/ https://ncbi.nlm.nih.gov/pubmed/28369584 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx191 |
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