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HIV-1 transcription is regulated by splicing factor SRSF1

Efficient transcription of the HIV-1 genome is regulated by Tat, which recruits P-TEFb from the 7SK small nuclear ribonucleoprotein (snRNP) and other nucleoplasmic complexes to phosphorylate RNA polymerase II and other factors associated with the transcription complex. Although Tat activity is depen...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Paz, Sean, Krainer, Adrian R., Caputi, Massimo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267630/
https://ncbi.nlm.nih.gov/pubmed/25416801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1170
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