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HIV-1 transcription is regulated by splicing factor SRSF1

Efficient transcription of the HIV-1 genome is regulated by Tat, which recruits P-TEFb from the 7SK small nuclear ribonucleoprotein (snRNP) and other nucleoplasmic complexes to phosphorylate RNA polymerase II and other factors associated with the transcription complex. Although Tat activity is depen...

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Bibliografische gegevens
Gepubliceerd in:Nucleic Acids Res
Hoofdauteurs: Paz, Sean, Krainer, Adrian R., Caputi, Massimo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267630/
https://ncbi.nlm.nih.gov/pubmed/25416801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1170
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