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HIV-1 transcription is regulated by splicing factor SRSF1

Efficient transcription of the HIV-1 genome is regulated by Tat, which recruits P-TEFb from the 7SK small nuclear ribonucleoprotein (snRNP) and other nucleoplasmic complexes to phosphorylate RNA polymerase II and other factors associated with the transcription complex. Although Tat activity is depen...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Paz, Sean, Krainer, Adrian R., Caputi, Massimo
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267630/
https://ncbi.nlm.nih.gov/pubmed/25416801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1170
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