Tigecycline suppresses toxin A and B production and sporulation in Clostridium difficile

BACKGROUND: Clostridium difficile infection (CDI) is mediated by potent extracellular toxins and is spread largely via bacterial spores. We and others have shown that some antibiotics stimulate C. difficile toxin production in a strain-specific manner; however, the effects of newer anti-C. difficile...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Antimicrob Chemother
Main Authors: Aldape, Michael John, Heeney, Dustin Delaney, Bryant, Amy Evelyn, Stevens, Dennis Leroy
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2015
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267498/
https://ncbi.nlm.nih.gov/pubmed/25151204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dku325
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