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Characterization of the Sporulation Initiation Pathway of Clostridium difficile and Its Role in Toxin Production

Clostridium difficile is responsible for significant mortality and morbidity in the hospitalized elderly. C. difficile spores are infectious and are a major factor contributing to nosocomial transmission. The Spo0A response regulator is the master regulator for sporulation initiation and can influen...

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Detalhes bibliográficos
Main Authors: Underwood, Sarah, Guan, Shuang, Vijayasubhash, Vinod, Baines, Simon D., Graham, Luke, Lewis, Richard J., Wilcox, Mark H., Stephenson, Keith
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786572/
https://ncbi.nlm.nih.gov/pubmed/19783633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00882-09
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