Characterization of the Sporulation Initiation Pathway of Clostridium difficile and Its Role in Toxin Production

Clostridium difficile is responsible for significant mortality and morbidity in the hospitalized elderly. C. difficile spores are infectious and are a major factor contributing to nosocomial transmission. The Spo0A response regulator is the master regulator for sporulation initiation and can influen...

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Bibliografiska uppgifter
Huvudupphovsmän: Underwood, Sarah, Guan, Shuang, Vijayasubhash, Vinod, Baines, Simon D., Graham, Luke, Lewis, Richard J., Wilcox, Mark H., Stephenson, Keith
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology (ASM) 2009
Ämnen:
Molecular Biology of Pathogens
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2786572/
https://ncbi.nlm.nih.gov/pubmed/19783633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00882-09
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