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Tigecycline suppresses toxin A and B production and sporulation in Clostridium difficile

BACKGROUND: Clostridium difficile infection (CDI) is mediated by potent extracellular toxins and is spread largely via bacterial spores. We and others have shown that some antibiotics stimulate C. difficile toxin production in a strain-specific manner; however, the effects of newer anti-C. difficile...

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Podrobná bibliografie
Vydáno v:J Antimicrob Chemother
Hlavní autoři: Aldape, Michael John, Heeney, Dustin Delaney, Bryant, Amy Evelyn, Stevens, Dennis Leroy
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267498/
https://ncbi.nlm.nih.gov/pubmed/25151204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dku325
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