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Tigecycline suppresses toxin A and B production and sporulation in Clostridium difficile

BACKGROUND: Clostridium difficile infection (CDI) is mediated by potent extracellular toxins and is spread largely via bacterial spores. We and others have shown that some antibiotics stimulate C. difficile toxin production in a strain-specific manner; however, the effects of newer anti-C. difficile...

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Pubblicato in:J Antimicrob Chemother
Autori principali: Aldape, Michael John, Heeney, Dustin Delaney, Bryant, Amy Evelyn, Stevens, Dennis Leroy
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267498/
https://ncbi.nlm.nih.gov/pubmed/25151204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dku325
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