Tigecycline suppresses toxin A and B production and sporulation in Clostridium difficile

BACKGROUND: Clostridium difficile infection (CDI) is mediated by potent extracellular toxins and is spread largely via bacterial spores. We and others have shown that some antibiotics stimulate C. difficile toxin production in a strain-specific manner; however, the effects of newer anti-C. difficile...

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發表在:J Antimicrob Chemother
Main Authors: Aldape, Michael John, Heeney, Dustin Delaney, Bryant, Amy Evelyn, Stevens, Dennis Leroy
格式: Artigo
語言:Inglês
出版: Oxford University Press 2015
主題:
Original Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267498/
https://ncbi.nlm.nih.gov/pubmed/25151204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dku325
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