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Tigecycline suppresses toxin A and B production and sporulation in Clostridium difficile

BACKGROUND: Clostridium difficile infection (CDI) is mediated by potent extracellular toxins and is spread largely via bacterial spores. We and others have shown that some antibiotics stimulate C. difficile toxin production in a strain-specific manner; however, the effects of newer anti-C. difficile...

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Detalhes bibliográficos
Publicado no:J Antimicrob Chemother
Main Authors: Aldape, Michael John, Heeney, Dustin Delaney, Bryant, Amy Evelyn, Stevens, Dennis Leroy
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267498/
https://ncbi.nlm.nih.gov/pubmed/25151204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dku325
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