Substrate recognition by the cell surface palmitoyl transferase DHHC5

The cardiac phosphoprotein phospholemman (PLM) regulates the cardiac sodium pump, activating the pump when phosphorylated and inhibiting it when palmitoylated. Protein palmitoylation, the reversible attachment of a 16 carbon fatty acid to a cysteine thiol, is catalyzed by the Asp-His-His-Cys (DHHC)...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Howie, Jacqueline, Reilly, Louise, Fraser, Niall J., Vlachaki Walker, Julia M., Wypijewski, Krzysztof J., Ashford, Michael L. J., Calaghan, Sarah C., McClafferty, Heather, Tian, Lijun, Shipston, Michael J., Boguslavskyi, Andrii, Shattock, Michael J., Fuller, William
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267385/
https://ncbi.nlm.nih.gov/pubmed/25422474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1413627111
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