Chargement en cours...
Dynamic changes in E-protein activity regulate T reg cell development
E-proteins are TCR-sensitive transcription factors essential for intrathymic T cell transitions. Here, we show that deletion of E-proteins leads to both enhanced peripheral TGF-β–induced regulatory T (iT reg) cell and thymic naturally arising T reg cell (nT reg cell) differentiation. In contrast, de...
Enregistré dans:
| Publié dans: | J Exp Med |
|---|---|
| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Rockefeller University Press
2014
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4267236/ https://ncbi.nlm.nih.gov/pubmed/25488982 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20132681 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|