Proteasome inhibition slightly improves cardiac function in mice with hypertrophic cardiomyopathy

A growing line of evidence indicates a dysfunctional ubiquitin-proteasome system (UPS) in cardiac diseases. Anti-hypertrophic effects and improved cardiac function have been reported after treatment with proteasome inhibitors in experimental models of cardiac hypertrophy. Here we tested whether prot...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Schlossarek, Saskia, Singh, Sonia R., Geertz, Birgit, Schulz, Herbert, Reischmann, Silke, Hübner, Norbert, Carrier, Lucie
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267180/
https://ncbi.nlm.nih.gov/pubmed/25566086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2014.00484
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