The catalytic subunit of DNA-dependent protein kinase is required for cellular resistance to oxidative stress independent of DNA double strand break repair

DNA-dependent protein kinase catalytic subunit (DNA-PKcs) and Ataxia telangiectasia mutated (ATM) are the two major kinases involved in DNA double-strand break (DSB) repair, and are required for cellular resistance to ionizing radiation. While ATM is the key upstream kinase for DSB signaling, DNA-PK...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Free Radic Biol Med
Autores principales: Li, Mengxia, Lin, Yu-Fen, Palchik, Guillermo, Matsunaga, Shinji, Wang, Dong, Chen, Benjamin P.C.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267055/
https://ncbi.nlm.nih.gov/pubmed/25224041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2014.08.019
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares