Néstor-Guillermo Progeria Syndrome: a biochemical insight into Barrier-to-Autointegration Factor 1, alanine 12 threonine mutation

BACKGROUND: Premature aging syndromes recapitulate many aspects of natural aging and provide an insight into this phenomenon at a molecular and cellular level. The progeria syndromes appear to cause rapid aging through disruption of normal nuclear structure. Recently, a coding mutation (c.34G > A...

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Veröffentlicht in:BMC Mol Biol
Hauptverfasser: Paquet, Nicolas, Box, Joseph K, Ashton, Nicholas W, Suraweera, Amila, Croft, Laura V, Urquhart, Aaron J, Bolderson, Emma, Zhang, Shu-Dong, O’Byrne, Kenneth J, Richard, Derek J
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4266902/
https://ncbi.nlm.nih.gov/pubmed/25495845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12867-014-0027-z
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