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Targeting SR Proteins Improves SMN Expression in Spinal Muscular Atrophy Cells

Spinal muscular atrophy (SMA) is one of the most common inherited causes of pediatric mortality. SMA is caused by deletions or mutations in the survival of motor neuron 1 (SMN1) gene, which results in SMN protein deficiency. Humans have a centromeric copy of the survival of motor neuron gene, SMN2,...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Wee, Claribel D., Havens, Mallory A., Jodelka, Francine M., Hastings, Michelle L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4266657/
https://ncbi.nlm.nih.gov/pubmed/25506695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115205
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