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Therapy Development for Spinal Muscular Atrophy in SMN Independent Targets
Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disorder, leading to progressive muscle weakness, atrophy, and sometimes premature death. SMA is caused by mutation or deletion of the survival motor neuron-1 (SMN1) gene. An effective treatment does not presently exist. Since...
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Hindawi Publishing Corporation
2012
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3369530/ https://ncbi.nlm.nih.gov/pubmed/22701806 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/456478 |
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