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Therapy Development for Spinal Muscular Atrophy in SMN Independent Targets
Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disorder, leading to progressive muscle weakness, atrophy, and sometimes premature death. SMA is caused by mutation or deletion of the survival motor neuron-1 (SMN1) gene. An effective treatment does not presently exist. Since...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Hindawi Publishing Corporation
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3369530/ https://ncbi.nlm.nih.gov/pubmed/22701806 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/456478 |
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