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Therapy Development for Spinal Muscular Atrophy in SMN Independent Targets

Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disorder, leading to progressive muscle weakness, atrophy, and sometimes premature death. SMA is caused by mutation or deletion of the survival motor neuron-1 (SMN1) gene. An effective treatment does not presently exist. Since...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser: Tsai, Li-Kai
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369530/
https://ncbi.nlm.nih.gov/pubmed/22701806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/456478
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