ADH1B and ADH1C Genotype, Alcohol Consumption and Biomarkers of Liver Function: Findings from a Mendelian Randomization Study in 58,313 European Origin Danes

BACKGROUND: The effect of alcohol consumption on liver function is difficult to determine because of reporting bias and potential residual confounding. Our aim was to determine this effect using genetic variants to proxy for the unbiased effect of alcohol. METHODS: We used variants in ADH1B and ADH1...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Lawlor, Debbie A., Benn, Marianne, Zuccolo, Luisa, De Silva, N. Maneka G., Tybjaerg-Hansen, Anne, Smith, George Davey, Nordestgaard, Børge G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2014
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4266606/
https://ncbi.nlm.nih.gov/pubmed/25503943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114294
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