Role of mitogen-activated protein kinase phosphatase-1 in corticosteroid insensitivity of chronic oxidant lung injury

Oxidative stress plays an important role in the pathogenesis of chronic obstructive pulmonary disease (COPD) and in the induction of corticosteroid (CS) insensitivity. Chronic ozone exposure leads to a model of COPD with lung inflammation and emphysema. Mitogen-activated protein kinase phosphatase-1...

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Detalhes bibliográficos
Publicado no:Eur J Pharmacol
Main Authors: Pinart, Mariona, Hussain, Farhana, Shirali, Sima, Li, Feng, Zhu, Jie, Clark, Andrew R., Ammit, Alaina J., Chung, Kian Fan
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science 2014
Assuntos:
Pulmonary, Gastrointestinal and Urogenital Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4266539/
https://ncbi.nlm.nih.gov/pubmed/25310910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2014.10.003
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