Corticosteroids and β(2)-agonists upregulate mitogen-activated protein kinase phosphatase 1: in vitro mechanisms

BACKGROUND AND PURPOSE: Airway remodelling is a consequence of long-term inflammation and MAPKs are key signalling molecules that drive pro-inflammatory pathways. The endogenous MAPK deactivator – MAPK phosphatase 1 (MKP-1) – is a critical negative regulator of the myriad pro-inflammatory pathways a...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Manetsch, M, Ramsay, EE, King, EM, Seidel, P, Che, W, Ge, Q, Hibbs, DE, Newton, R, Ammit, AJ
Materialtyp: Artigo
Språk:Inglês
Publicerad: Blackwell Publishing Ltd 2012
Ämnen:
Research Papers
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402770/
https://ncbi.nlm.nih.gov/pubmed/22372570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2012.01923.x
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk