Cyclin D1 in ASM Cells from Asthmatics Is Insensitive to Corticosteroid Inhibition

Hyperplasia of airway smooth muscle (ASM) is a feature of the remodelled airway in asthmatics. We examined the antiproliferative effectiveness of the corticosteroid dexamethasone on expression of the key regulator of G(1) cell cycle progression—cyclin D1—in ASM cells from nonasthmatics and asthmatic...

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Bibliografiske detaljer
Main Authors: Allen, Jodi C., Seidel, Petra, Schlosser, Tobias, Ramsay, Emma E., Ge, Qi, Ammit, Alaina J.
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3303636/
https://ncbi.nlm.nih.gov/pubmed/22500182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/307838
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