Cyclin D1 in ASM Cells from Asthmatics Is Insensitive to Corticosteroid Inhibition

Hyperplasia of airway smooth muscle (ASM) is a feature of the remodelled airway in asthmatics. We examined the antiproliferative effectiveness of the corticosteroid dexamethasone on expression of the key regulator of G(1) cell cycle progression—cyclin D1—in ASM cells from nonasthmatics and asthmatic...

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Detalhes bibliográficos
Main Authors: Allen, Jodi C., Seidel, Petra, Schlosser, Tobias, Ramsay, Emma E., Ge, Qi, Ammit, Alaina J.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3303636/
https://ncbi.nlm.nih.gov/pubmed/22500182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/307838
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