Regulation of Melanin Synthesis in Mammalian Cells: Effect of Gene Dosage on the Expression of Differentiation
Near-tetraploid (2S), pigmented, Syrian hamster cells (3460(2)) were hybridized with unpigmented mouse fibroblasts to produce hybrids that contained two pigment cell genomes and one fibroblast genome per cell (3(2)D). Half of the hybrids were pigmented and showed high activity of the enzyme dihydrox...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| 1. Verfasser: | |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1972
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| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC426602/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4623665/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.69.4.951 |
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