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Regulation of Melanin Synthesis in Mammalian Cells: Effect of Gene Dosage on the Expression of Differentiation

Near-tetraploid (2S), pigmented, Syrian hamster cells (3460(2)) were hybridized with unpigmented mouse fibroblasts to produce hybrids that contained two pigment cell genomes and one fibroblast genome per cell (3(2)D). Half of the hybrids were pigmented and showed high activity of the enzyme dihydrox...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autor Principal: Davidson, Richard L.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1972
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC426602/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4623665/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.69.4.951
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