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Enhancement of DNA Synthesis in a Mammalian Cell-Free System by Trypsin Treatment

DNA synthesis in a broken cellular preparation of Chinese hamster cells was enhanced approximately 10-fold by a brief trypsin treatment. Alphachymotrypsin also enhanced the synthesis, whereas Pronase did not. The trypsin appears to be acting on a component of the nucleus. Evidence suggests that the...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Brown, Ronald L., Stubblefield, Elton
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1974
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC388471/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4526218/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.6.2432
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