GSK-3β Inhibition Attenuates CLP-Induced Liver Injury by Reducing Inflammation and Hepatic Cell Apoptosis

Liver dysfunction has been known to occur frequently in cases of sepsis. Excessive inflammation and apoptosis are pathological features of acute liver failure. Recent studies suggest that activation of glycogen synthase kinase- (GSK-) 3β is involved in inflammation and apoptosis. We aimed to investi...

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Vydáno v:Mediators Inflamm
Hlavní autoři: Zhang, Hui, Wang, Wenjie, Fang, Haoshu, Yang, Yan, Li, Xiaolan, He, Junli, Jiang, Xiaojing, Wang, Weipeng, Liu, Shenpei, Hu, Jifa, Liu, Anding, Dahmen, Uta, Dirsch, Olaf
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2014
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4265684/
https://ncbi.nlm.nih.gov/pubmed/25525303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/629507
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