GSK-3β Inhibition Attenuates CLP-Induced Liver Injury by Reducing Inflammation and Hepatic Cell Apoptosis

Liver dysfunction has been known to occur frequently in cases of sepsis. Excessive inflammation and apoptosis are pathological features of acute liver failure. Recent studies suggest that activation of glycogen synthase kinase- (GSK-) 3β is involved in inflammation and apoptosis. We aimed to investi...

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Enregistré dans:
Détails bibliographiques
Publié dans:Mediators Inflamm
Auteurs principaux: Zhang, Hui, Wang, Wenjie, Fang, Haoshu, Yang, Yan, Li, Xiaolan, He, Junli, Jiang, Xiaojing, Wang, Weipeng, Liu, Shenpei, Hu, Jifa, Liu, Anding, Dahmen, Uta, Dirsch, Olaf
Format: Artigo
Langue:Inglês
Publié: Hindawi Publishing Corporation 2014
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4265684/
https://ncbi.nlm.nih.gov/pubmed/25525303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/629507
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