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Granulocyte Colony Stimulating Factor Induces Lipopolysaccharide (LPS) Sensitization via Upregulation of LPS Binding Protein in Rat

Liver is the main organ for lipopolysaccharide (LPS) clearance. Sensitization to LPS is associated with the upregulation of LPS-binding protein (LBP) in animal models. Therefore, we hypothesized that LBP could induce LPS sensitization through enhancing hepatic uptake of LPS. In this study, we examin...

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Bibliographic Details
Main Authors: Fang, Haoshu, Liu, Anding, Sun, Jian, Kitz, Alexandra, Dirsch, Olaf, Dahmen, Uta
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3577878/
https://ncbi.nlm.nih.gov/pubmed/23437199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056654
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