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Inhibition of Neutrophil Collagenase/MMP-8 and Gelatinase B/MMP-9 and Protection against Endotoxin Shock

Endotoxin shock is a life-threatening disorder, associated with the rapid release of neutrophil enzymes, including neutrophil collagenase/matrix metalloproteinase-8 (MMP-8) and gelatinase B/matrix metalloproteinase-9 (MMP-9). After activation, these enzymes cleave extracellular matrix components and...

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Publicado en:J Immunol Res
Autores principales: Qiu, Zheng, Chen, Jianghai, Xu, Hanmei, Van den Steen, Philippe E., Opdenakker, Ghislain, Wang, Min, Hu, Jialiang
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi Publishing Corporation 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4265539/
https://ncbi.nlm.nih.gov/pubmed/25762310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/747426
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