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Functional and Evolutionary Significance of Human MicroRNA Seed Region Mutations

MicroRNAs have emerged in recent years as important regulators of cell function in both normal and diseased cells. MiRNAs coordinately regulate large suites of target genes by mRNA degradation and/or translational inhibition. The mRNA target specificities of miRNAs in animals are primarily encoded w...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Hill, Christopher G., Jabbari, Neda, Matyunina, Lilya V., McDonald, John F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4264867/
https://ncbi.nlm.nih.gov/pubmed/25501359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115241
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