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Functional and Evolutionary Significance of Human MicroRNA Seed Region Mutations

MicroRNAs have emerged in recent years as important regulators of cell function in both normal and diseased cells. MiRNAs coordinately regulate large suites of target genes by mRNA degradation and/or translational inhibition. The mRNA target specificities of miRNAs in animals are primarily encoded w...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Hill, Christopher G., Jabbari, Neda, Matyunina, Lilya V., McDonald, John F.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4264867/
https://ncbi.nlm.nih.gov/pubmed/25501359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115241
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