Evidence for the Complexity of MicroRNA-Mediated Regulation in Ovarian Cancer: A Systems Approach

MicroRNAs (miRNAs) are short (∼22 nucleotides) regulatory RNAs that can modulate gene expression and are aberrantly expressed in many diseases including cancer. Previous studies have shown that miRNAs inhibit the translation and facilitate the degradation of their targeted messenger RNAs (mRNAs) mak...

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Главные авторы: Shahab, Shubin W., Matyunina, Lilya V., Mezencev, Roman, Walker, L. DeEtte, Bowen, Nathan J., Benigno, Benedict B., McDonald, John F.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2011
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3141058/
https://ncbi.nlm.nih.gov/pubmed/21811625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022508
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