Evidence for the Complexity of MicroRNA-Mediated Regulation in Ovarian Cancer: A Systems Approach

MicroRNAs (miRNAs) are short (∼22 nucleotides) regulatory RNAs that can modulate gene expression and are aberrantly expressed in many diseases including cancer. Previous studies have shown that miRNAs inhibit the translation and facilitate the degradation of their targeted messenger RNAs (mRNAs) mak...

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Detalhes bibliográficos
Main Authors: Shahab, Shubin W., Matyunina, Lilya V., Mezencev, Roman, Walker, L. DeEtte, Bowen, Nathan J., Benigno, Benedict B., McDonald, John F.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3141058/
https://ncbi.nlm.nih.gov/pubmed/21811625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022508
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