Evidence for the Complexity of MicroRNA-Mediated Regulation in Ovarian Cancer: A Systems Approach

MicroRNAs (miRNAs) are short (∼22 nucleotides) regulatory RNAs that can modulate gene expression and are aberrantly expressed in many diseases including cancer. Previous studies have shown that miRNAs inhibit the translation and facilitate the degradation of their targeted messenger RNAs (mRNAs) mak...

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Bibliografiske detaljer
Main Authors: Shahab, Shubin W., Matyunina, Lilya V., Mezencev, Roman, Walker, L. DeEtte, Bowen, Nathan J., Benigno, Benedict B., McDonald, John F.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3141058/
https://ncbi.nlm.nih.gov/pubmed/21811625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022508
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