Gene expression profiling supports the hypothesis that human ovarian surface epithelia are multipotent and capable of serving as ovarian cancer initiating cells

BACKGROUND: Accumulating evidence suggests that somatic stem cells undergo mutagenic transformation into cancer initiating cells. The serous subtype of ovarian adenocarcinoma in humans has been hypothesized to arise from at least two possible classes of progenitor cells: the ovarian surface epitheli...

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Detalhes bibliográficos
Main Authors: Bowen, Nathan J, Walker, L DeEtte, Matyunina, Lilya V, Logani, Sanjay, Totten, Kimberly A, Benigno, Benedict B, McDonald, John F
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806370/
https://ncbi.nlm.nih.gov/pubmed/20040092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-2-71
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