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Regulation of Adenosine 3′:5′-Cyclic Monophosphate Phosphodiesterase Activity in Fibroblasts by Intracellular Concentrations of Cyclic Adenosine Monophosphate
Cyclic AMP-phosphodiesterase is present in various mouse fibroblasts. Contact-inhibited 3T3 cells contain two forms of the enzyme, one with a K(m) of 2.5 μM and the second with a K(m) of 71 μM. As 3T3 cells grow to confluency and cAMP concentrations rise, the activity of the first enzyme increases,...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
1972
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC426480/ https://ncbi.nlm.nih.gov/pubmed/4333987 |
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