Regulation of Adenosine 3′:5′-Cyclic Monophosphate Phosphodiesterase Activity in Fibroblasts by Intracellular Concentrations of Cyclic Adenosine Monophosphate
Cyclic AMP-phosphodiesterase is present in various mouse fibroblasts. Contact-inhibited 3T3 cells contain two forms of the enzyme, one with a K(m) of 2.5 μM and the second with a K(m) of 71 μM. As 3T3 cells grow to confluency and cAMP concentrations rise, the activity of the first enzyme increases,...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1972
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC426480/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4333987/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.69.2.459 |
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