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Peptide Targeting of Fluorescein-Based Sensors to Discrete Intracellular Locales

Fluorescein-based sensors are the most widely applied class of zinc probes but display adventitious localization in live cells. We present here a peptide-based localization strategy that affords precision in targeting of fluorescein-based zinc sensors. By appending the zinc-selective, reaction-based...

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Bibliographic Details
Published in:Chem Sci
Main Authors: Radford, Robert J., Chyan, Wen, Lippard, Stephen J.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4264632/
https://ncbi.nlm.nih.gov/pubmed/25512838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C4SC01280A
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