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Reaction-based fluorescent sensor for investigating mobile Zn(2+) in mitochondria of healthy versus cancerous prostate cells

Chelatable, mobile forms of divalent zinc, Zn(II), play essential signaling roles in mammalian biology. A complex network of zinc import and transport proteins has evolved to control zinc concentration and distribution on a subcellular level. Understanding the action of mobile zinc requires tools th...

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Detalhes bibliográficos
Main Authors: Chyan, Wen, Zhang, Daniel Y., Lippard, Stephen J., Radford, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3890804/
https://ncbi.nlm.nih.gov/pubmed/24335702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1310583110
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