Chargement en cours...
Functional characterization of the TERRA transcriptome at damaged telomeres
Telomere deprotection occurs during tumorigenesis and aging upon telomere shortening or loss of the telomeric shelterin component TRF2. Deprotected telomeres undergo changes in chromatin structure and elicit a DNA damage response (DDR) that leads to cellular senescence. The telomeric long noncoding...
Enregistré dans:
| Publié dans: | Nat Commun |
|---|---|
| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2014
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4264578/ https://ncbi.nlm.nih.gov/pubmed/25359189 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6379 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|