Cooperative action of cellular proteins YB-1 and Pur alpha with the tumor antigen of the human JC polyomavirus determines their interaction with the viral lytic control element.

Human JC polyomavirus (JCV) is the etiologic agent of the neurodegenerative disease progressive mulifocal leukoencephalopathy. By using JCV as a model, we investigated the role of the viral early protein tumor antigen (TAg) in the binding of two cellular proteins, Pura alpha and YB-1, to JCV regulat...

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Hlavní autoři: Chen, N N, Chang, C F, Gallia, G L, Kerr, D A, Johnson, E M, Krachmarov, C P, Barr, S M, Frisque, R J, Bollag, B, Khalili, K
Médium: Artigo
Jazyk:Inglês
Vydáno: 1995
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC42642/
https://ncbi.nlm.nih.gov/pubmed/7862639
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