Cooperative action of cellular proteins YB-1 and Pur alpha with the tumor antigen of the human JC polyomavirus determines their interaction with the viral lytic control element.

Human JC polyomavirus (JCV) is the etiologic agent of the neurodegenerative disease progressive mulifocal leukoencephalopathy. By using JCV as a model, we investigated the role of the viral early protein tumor antigen (TAg) in the binding of two cellular proteins, Pura alpha and YB-1, to JCV regulat...

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Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Chen, N N, Chang, C F, Gallia, G L, Kerr, D A, Johnson, E M, Krachmarov, C P, Barr, S M, Frisque, R J, Bollag, B, Khalili, K
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 1995
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42642/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7862639/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.4.1087
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