Cooperative action of cellular proteins YB-1 and Pur alpha with the tumor antigen of the human JC polyomavirus determines their interaction with the viral lytic control element.

Human JC polyomavirus (JCV) is the etiologic agent of the neurodegenerative disease progressive mulifocal leukoencephalopathy. By using JCV as a model, we investigated the role of the viral early protein tumor antigen (TAg) in the binding of two cellular proteins, Pura alpha and YB-1, to JCV regulat...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Chen, N N, Chang, C F, Gallia, G L, Kerr, D A, Johnson, E M, Krachmarov, C P, Barr, S M, Frisque, R J, Bollag, B, Khalili, K
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42642/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7862639/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.4.1087
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