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Multiple Mechanisms Mediate Resistance to Sorafenib in Urothelial Cancer
Genetic and epigenetic changes in the mitogen activated protein kinase (MAPK) signaling render urothelial cancer a potential target for tyrosine kinase inhibitor (TKI) treatment. However, clinical trials of several TKIs failed to prove efficacy. In this context, we investigated changes in MAPK signa...
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| Publicado en: | Int J Mol Sci |
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| Autores principales: | , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
MDPI
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4264180/ https://ncbi.nlm.nih.gov/pubmed/25387078 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms151120500 |
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