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HERV-K and LINE-1 DNA Methylation and Reexpression in Urothelial Carcinoma

Changes in DNA methylation frequently accompany cancer development. One prominent change is an apparently genome-wide decrease in methylcytosine that is often ascribed to DNA hypomethylation at retroelements comprising nearly half the genome. DNA hypomethylation may allow reactivation of retroelemen...

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Detalhes bibliográficos
Main Authors: Kreimer, Ulrike, Schulz, Wolfgang A., Koch, Annemarie, Niegisch, Günter, Goering, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3783855/
https://ncbi.nlm.nih.gov/pubmed/24133654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2013.00255
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