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Two functional loci in the promoter of EPAS1 gene involved in high-altitude adaptation of Tibetans

EPAS1 involves in the hypoxic response and is suggested to be responsible for the genetic adaptation of high-altitude hypoxia in Tibetans. However, the detailed molecular mechanism remains unknown. In this study, a single nucleotide polymorphism rs56721780:G>C and an insertion/deletion (indel) po...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Xu, Xiang-Hong, Huang, Xue-Wen, Qun, Li, Li, Ya-Nan, Wang, Yi, Liu, Chao, Ma, Yanyun, Liu, Qing-Mei, Sun, Kang, Qian, Feng, Jin, Li, Wang, Jiucun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4264014/
https://ncbi.nlm.nih.gov/pubmed/25501874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep07465
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