EPAS1 Gain-of-Function Mutation Contributes to High-Altitude Adaptation in Tibetan Horses

High altitude represents some of the most extreme environments worldwide. The genetic changes underlying adaptation to such environments have been recently identified in multiple animals but remain unknown in horses. Here, we sequence the complete genome of 138 domestic horses encompassing a whole a...

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Gepubliceerd in:Mol Biol Evol
Hoofdauteurs: Liu, Xuexue, Zhang, Yanli, Li, Yefang, Pan, Jianfei, Wang, Dandan, Chen, Weihuang, Zheng, Zhuqing, He, Xiaohong, Zhao, Qianjun, Pu, Yabin, Guan, Weijun, Han, Jianlin, Orlando, Ludovic, Ma, Yuehui, Jiang, Lin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2019
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Discoveries
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6805228/
https://ncbi.nlm.nih.gov/pubmed/31273382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msz158
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