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p38α (MAPK14) critically regulates the immunological response and the production of specific cytokines and chemokines in astrocytes

In CNS lesions, “reactive astrocytes” form a prominent cellular response. However, the nature of this astrocyte immune activity is not well understood. In order to study astrocytic immune responses to inflammation and injury, we generated mice with conditional deletion of p38α (MAPK14) in GFAP+ astr...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lo, U., Selvaraj, V., Plane, J. M., Chechneva, O. V., Otsu, K., Deng, W.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4264013/
https://ncbi.nlm.nih.gov/pubmed/25502009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep07405
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