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p38α (MAPK14) critically regulates the immunological response and the production of specific cytokines and chemokines in astrocytes

In CNS lesions, “reactive astrocytes” form a prominent cellular response. However, the nature of this astrocyte immune activity is not well understood. In order to study astrocytic immune responses to inflammation and injury, we generated mice with conditional deletion of p38α (MAPK14) in GFAP+ astr...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Lo, U., Selvaraj, V., Plane, J. M., Chechneva, O. V., Otsu, K., Deng, W.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4264013/
https://ncbi.nlm.nih.gov/pubmed/25502009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep07405
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