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The Emerging Link between O-GlcNAc and Alzheimer Disease
Regional glucose hypometabolism is a defining feature of Alzheimer disease (AD). One emerging link between glucose hypometabolism and progression of AD is the nutrient-responsive post-translational O-GlcNAcylation of nucleocytoplasmic proteins. O-GlcNAc is abundant in neurons and occurs on both tau...
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Publicado no: | J Biol Chem |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4263855/ https://ncbi.nlm.nih.gov/pubmed/25336656 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R114.601351 |
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