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O-GlcNAc and the Epigenetic Regulation of Gene Expression

O-GlcNAcylation is an abundant nutrient-driven modification linked to cellular signaling and regulation of gene expression. Utilizing precursors derived from metabolic flux, O-GlcNAc functions as a homeostatic regulator. The enzymes of O-GlcNAc cycling, OGT and O-GlcNAcase, act in mitochondria, the...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Lewis, Brian A., Hanover, John A.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4263851/
https://ncbi.nlm.nih.gov/pubmed/25336654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R114.595439
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