Hypercytotoxicity and Rapid Loss of NKp44(+) Innate Lymphoid Cells during Acute SIV Infection

HIV/SIV infections break down the integrity of the gastrointestinal mucosa and lead to chronic immune activation and associated disease progression. Innate lymphoid cells (ILCs), distinguishable by high expression of NKp44 and RORγt, play key roles in mucosal defense and homeostasis, but are deplete...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Li, Haiying, Richert-Spuhler, Laura E., Evans, Tristan I., Gillis, Jacqueline, Connole, Michelle, Estes, Jacob D., Keele, Brandon F., Klatt, Nichole R., Reeves, R. Keith
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4263758/
https://ncbi.nlm.nih.gov/pubmed/25503264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004551
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