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Identification of a mitotic Rac-GEF, Trio, that counteracts MgcRacGAP function during cytokinesis

The Rho GTPases RhoA and Rac1 function as master regulators of cytokinesis by controlling the actomyosin cytoskeleton. RhoA and Rac1 have to be respectively activated and inactivated at the division plane for cytokinesis to occur properly. The inactivation of Rac1 at the cleavage furrow is controlle...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Biol Cell
Egile Nagusiak: Cannet, Aude, Schmidt, Susanne, Delaval, Bénédicte, Debant, Anne
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The American Society for Cell Biology 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4263449/
https://ncbi.nlm.nih.gov/pubmed/25355950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-06-1153
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