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Ect2 and MgcRacGAP regulate the activation and function of Cdc42 in mitosis

Although Rho regulates cytokinesis, little was known about the functions in mitosis of Cdc42 and Rac. We recently suggested that Cdc42 works in metaphase by regulating bi-orient attachment of spindle microtubules to kinetochores. We now confirm the role of Cdc42 by RNA interference and identify the...

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Détails bibliographiques
Auteurs principaux: Oceguera-Yanez, Fabian, Kimura, Kazuhiro, Yasuda, Shingo, Higashida, Chiharu, Kitamura, Toshio, Hiraoka, Yasushi, Haraguchi, Tokuko, Narumiya, Shuh
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171585/
https://ncbi.nlm.nih.gov/pubmed/15642749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200408085
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