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Identification of a mitotic Rac-GEF, Trio, that counteracts MgcRacGAP function during cytokinesis
The Rho GTPases RhoA and Rac1 function as master regulators of cytokinesis by controlling the actomyosin cytoskeleton. RhoA and Rac1 have to be respectively activated and inactivated at the division plane for cytokinesis to occur properly. The inactivation of Rac1 at the cleavage furrow is controlle...
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| 出版年: | Mol Biol Cell |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The American Society for Cell Biology
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4263449/ https://ncbi.nlm.nih.gov/pubmed/25355950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-06-1153 |
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